
The Ultimate Guide to Layering Serums: What Goes Where in Your Routine
July 16, 2025
Overview
Unlock the secrets to a radiant complexion with our ultimate guide to layering serums! Understanding how to correctly layer your skincare products is crucial for maximizing their effectiveness. This in-depth article breaks down the science behind serum application, explaining which ingredients work best together and in what order to apply them. Learn how to build a personalized serum routine tailored to your specific skin concerns, from anti-aging and hydration to brightening and acne treatment. Discover the key to unlocking your skin's potential and achieving your skincare goals with expert advice on serum layering.
Our picks
The Best Serum for Your Skin Type: C E Ferulic by SkinCeuticals, $185.00
The Best PM Routine for Overnight Repair: Advanced Night Repair Serum, $55.00
The Most Effective Anti-Aging Serum: RETINOL CORREXION Deep Wrinkle Serum, $21.99
The Best Brightening Serum for Radiant Skin: MULTI CORREXION Revive + Glow Daily Serum, $26.99
The Ultimate Serum Application Order Guide: Phyto Corrective Gel by SkinCeuticals, $85.00
The Easiest Way to Introduce New Serums: B-Hydra Serum by Drunk Elephant, $40.99
AM Routine: Serum Layering for Daytime Protection
The optimal order to apply serums for hydration, protection, and brightening.
6
Listful
Score
Clarify Serum
$12.00
Evulv Beauty's Clarify Serum is a budget-friendly option for those handling acne and redness, with a score of 6/10. This product includes niacinamide and hyaluronic acid, which we found helpful in soothing and hydrating skin. Be aware of its fragrance content and the use of benzyl alcohol, which may disturb sensitive skin. Despite these points, its plumping and calming properties offer real-world benefits for clearer, balanced skin.
The Good
• Contains niacinamide, known for its anti-inflammatory properties that help reduce redness and irritation.
• Includes hyaluronic acid, which provides deep hydration and plumps the skin.
The Bad
• Contains fragrance, which may cause irritation for sensitive skin types.
• Includes benzyl alcohol, which can be drying and irritating to the skin.
Key Active Ingredients: Hyaluronic Acid,Botanicals / Targeted Skin Concerns: Acne treatment,Redness,Sensitivity / Fragrance Free: false / Vegan: true
PM Routine: Nighttime Serum Application Strategies
Discover the best serum combinations for repair and rejuvenation while you sleep.
8.5
Listful
Score
Advanced Night Repair Serum
$55.00
Advanced Night Repair Serum by Estée Lauder offers a powerful anti-aging boost, earning an impressive 8.5/10 in our ratings. This serum deeply hydrates, leaving skin feeling soft and renewed by morning. While some find its scent off-putting and the cost higher relative to alternatives, its ability to improve skin's appearance is remarkable. Enjoy a refreshed and radiant look, perfect for various skin types, from dry to combination.
The Good
• Effectively hydrates and plumps the skin, leaving it feeling soft and supple.
• Lightweight formula absorbs quickly without leaving a greasy residue.
• Suitable for various skin types, including dry and combination skin.
The Bad
• Some users find the product to be expensive compared to other serums.
• A few users have reported an unpleasant smell upon application.
• Some users did not notice significant improvements in their skin's appearance.
Key Active Ingredients: Hyaluronic Acid,Peptides / Targeted Skin Concerns: Anti-aging,Hydration / Fragrance Free: true / Vegan: false
6.5
Listful
Score
Clarifying Serum
$15.99
Enhance your clarity routine with the budget-friendly Clarifying Serum, featuring a thoughtful blend of PHA and zinc. During our review, this product proved effective at gentle exfoliation and unclogging pores, making it a great choice for those managing acne treatments. Scoring 6.5/10, users noted mixed results and occasional breakouts, but its affordability and vegan, dermatologist-tested formula still make it an intriguing option for those seeking to tackle acne without drying the skin.
The Good
• Contains PHA and zinc to gently exfoliate and unclog pores without drying the skin.
• Affordable price point for a clarifying serum.
The Bad
• Some users experienced breakouts or irritation after use.
• Not all users noticed significant improvements in skin clarity.
Key Active Ingredients: Botanicals / Targeted Skin Concerns: Acne treatment / Fragrance Free: true / Vegan: true
Hydration Heroes: Serums for Dry Skin
Deeply hydrating serums to quench thirsty skin and restore a healthy glow.
8
Listful
Score
CeraVe Hydrating Hyaluronic Acid Face Serum
$24.99
With a solid 8/10 rating, CeraVe's Hydrating Hyaluronic Acid Face Serum excels in providing effective hydration, perfect for sensitive skin. Our testing highlights its fast-absorbing gel-cream texture that nourishes without leaving a greasy residue. However, some users might find a slight stickiness despite its fragrance-free claim. Nevertheless, it's a reliable choice for maintaining skin's moisture balance at an accessible price point.
The Good
• Contains hyaluronic acid and ceramides that help restore the skin's natural barrier.
• Fragrance-free formula suitable for sensitive skin.
• Lightweight, gel-cream texture absorbs quickly without leaving a sticky residue.
The Bad
• Some users find the serum's texture slightly sticky or tacky upon application.
• A small percentage of users report a mild scent, despite being labeled fragrance-free.
• Some users did not see noticeable results after extended use.
Key Active Ingredients: Hyaluronic Acid / Targeted Skin Concerns: Hydration / Fragrance Free: true / Vegan: false
8.5
Listful
Score
Advanced Snail 96 Mucin Power Essence
$9.00
The Advanced Snail 96 Mucin Power Essence impresses with an 8.5/10 score, offering exceptional nourishment at only $9.00. Packed with 96.3% snail secretion filtrate, it’s praised for fading dark spots and improving texture. During our review, some users noted its tacky texture and time to dry. Still, its fragrance-free formula makes it a standout pick for those looking to rejuvenate their skincare routine affordably and effectively.
The Good
• Contains 96.3% snail secretion filtrate, providing rich nourishment and quick absorption.
• Free from fragrance and essential oils, making it suitable for sensitive skin.
• Helps to fade dark spots and improve skin texture.
The Bad
• Some users find the texture sticky and tacky upon application.
• May not provide sufficient hydration for very dry skin types.
• Takes a while to dry and can leave an oily appearance on the skin.
Key Active Ingredients: Hyaluronic Acid / Targeted Skin Concerns: Anti-aging,Hydration,Brightening / Fragrance Free: true / Vegan: false
7
Listful
Score
Hydrating B5 Gel by SkinCeuticals
$80.75
SkinCeuticals' Hydrating B5 Gel offers a high-quality hydrating experience, rated at 7/10, though its price may deter some. In our testing, its lightweight formula enriched with hyaluronic acid and vitamin B5 absorbed quickly and boosted moisture levels significantly. It's fragrance-free, ideal for sensitive skin, yet it's not a standalone moisturizer, so layering with other products is recommended. If hydration is your goal, consider this balanced choice despite its cost.
The Good
• Lightweight, non-greasy formula that absorbs quickly into the skin.
• Contains hyaluronic acid and vitamin B5 to enhance skin hydration.
• Fragrance-free, making it suitable for sensitive skin types.
The Bad
• Some users report skin irritation, including redness and itchiness.
• Expensive compared to other hydrating serums on the market.
• Not a replacement for a moisturizer; additional moisturizing products may be needed.
Key Active Ingredients: Hyaluronic Acid / Targeted Skin Concerns: Hydration / Fragrance Free: true / Vegan: false
7
Listful
Score
B-Hydra Serum by Drunk Elephant
$40.99
For a lightweight, hydrating addition to your routine, consider Drunk Elephant's B-Hydra Serum. Our review highlights its gentle, fragrance-free formula perfect for sensitive skin, boasting hyaluronic acid and peptides for anti-aging benefits. While it scored a 7/10, the higher price and difficulty accessing the last drops in its packaging were noted downsides. However, it remains a clean and effective choice for those not battling extremely dry skin.
The Good
• Lightweight and fast-absorbing, making it suitable for both morning and nighttime use.
• Fragrance-free formulation, beneficial for those with sensitive skin or fragrance allergies.
• Clean formula free from potentially harmful ingredients like parabens, sulfates, and phthalates.
The Bad
• High price point compared to other hydrating serums on the market.
• Packaging can be tricky to work with, making it challenging to get the last drops of product out.
• Not suitable for extremely dry skin types, as it may not provide enough moisture on its own.
Key Active Ingredients: Hyaluronic Acid,Peptides,Botanicals / Targeted Skin Concerns: Hydration,Anti-aging / Fragrance Free: true / Vegan: true
7.5
Listful
Score
Hydrance BOOST Serum
$39.00
Experience robust hydration with Hydrance BOOST Serum. With a 7.5/10 rating, we found this serum perfect for sensitive skin, containing hyaluronic acid and vitamin B3 to strengthen skin barriers. While its fragrance may be too strong for some, it's lightweight and fast-absorbing. It’s a superb option for tackling dehydration and preserving skin vitality, though pairing with an additional moisturizer is recommended for extremely dry skin.
The Good
• Lightweight, non-greasy texture absorbs quickly into the skin.
• Contains hyaluronic acid and vitamin B3 for enhanced hydration and skin barrier support.
• Suitable for sensitive skin without causing irritation.
The Bad
• Some users find the fragrance too strong and perfumey.
• May not provide sufficient hydration for extremely dry skin without additional moisturizer.
• A few users reported a sticky residue after application.
Key Active Ingredients: Hyaluronic Acid / Targeted Skin Concerns: Hydration / Fragrance Free: false / Vegan: true
9
Listful
Score
Phyto Corrective Gel by SkinCeuticals
$85.00
Phyto Corrective Gel from SkinCeuticals scored an impressive 9/10 in our review, celebrated for its effectiveness in reducing redness and enhancing radiance. While carrying a higher price, this dermatologist-tested formula combines soothing botanicals and hyaluronic acid, delivering powerful hydration. It soothes and calms even the most sensitive skin, offering a premier solution for anyone looking to brighten and balance their complexion despite its fragrance presence.
The Good
• Effectively reduces redness and hydrates the skin.
The Bad
• Some users find the product to be pricey.
• Contains fragrance, which may irritate sensitive skin.
Key Active Ingredients: Hyaluronic Acid,Botanicals / Targeted Skin Concerns: Hydration,Redness,Sensitivity / Fragrance Free: false / Vegan: false
Anti-Aging Elixirs: Combatting Fine Lines
Top serums for reducing wrinkles and promoting a youthful, radiant complexion.
7.5
Listful
Score
RETINOL CORREXION Deep Wrinkle Serum
$21.99
The RETINOL CORREXION Deep Wrinkle Serum stands out for its effectiveness in reducing wrinkles, earning a commendable 7.5/10 rating. In our testing, its lightweight formula showcased visible improvements on the forehead in just four weeks. However, fragrance-sensitive users should note its strong scent, which some might find overpowering. At $21.99, it balances affordability with efficacy, making it appealing to those targeting deep wrinkle correction without breaking the bank.
The Good
• Effectively reduces deep forehead wrinkles, leaving skin smoother.
The Bad
• Some users find the fragrance unpleasant and overpowering.
• The product's scent is strong and may be off-putting to some users.
Key Active Ingredients: Retinol / Targeted Skin Concerns: Anti-aging / Fragrance Free: false / Vegan: false
8
Listful
Score
Micro-Dose Retinol Serum
$65.00
Kiehl's Micro-Dose Retinol Serum is an excellent choice for sensitive skin users seeking anti-aging benefits. Scoring 8/10 in our testing, this gentle retinol formulation reduces fine lines while improving texture, thanks to its non-sticky, fast-absorbing formula. While certain users experienced mild dryness, its balanced approach minimizes risk of irritation, making it ideal for those ready to incorporate retinol into their skincare routine.
The Good
• Gentle formulation suitable for sensitive skin.
• Improves skin texture and reduces fine lines.
• Non-sticky and absorbs quickly.
The Bad
• Some users experience mild peeling and dryness.
• Results may take several weeks to become noticeable.
• Higher price point compared to similar products.
Key Active Ingredients: Retinol,Peptides / Targeted Skin Concerns: Anti-aging / Fragrance Free: true / Vegan: false
7.5
Listful
Score
0.3% Retinol + 2% Bakuchiol Treatment
$65.00
For those searching for anti-aging advancements, the 0.3% Retinol + 2% Bakuchiol Treatment is a must-try, scoring 7.5/10 in our analysis. This serum combines retinol and bakuchiol to target fine lines and enhance brightness, supported by peptides for added skin firming. Be mindful of potential dryness and difficulties with its dispenser. Despite these issues, it's a robust formula improving texture and promoting a youthful appearance with continued use.
The Good
• Combines retinol and bakuchiol for enhanced anti-aging benefits.
The Bad
• Some users report difficulty dispensing product due to packaging design.
• May cause dryness or irritation for those with sensitive skin.
Key Active Ingredients: Retinol,Bakuchiol,Peptides / Targeted Skin Concerns: Anti-aging,Brightening / Fragrance Free: true / Vegan: true
7.5
Listful
Score
Olay Retinol 24 Night Serum
$29.99
Transform your nighttime skincare routine with Olay Retinol 24 Night Serum, a solution that targets anti-aging, hydration, and brightening needs. In our testing, its fragrance-free and lightweight formula, featuring retinol and niacinamide, was gentle on sensitive skin but took several weeks to show noticeable results. Despite a 7.5/10 rating due to some packaging issues and potential eye sensitivity, it remains an accessible option under $30 for a smoother, more youthful complexion.
The Good
• Lightweight, non-greasy texture that absorbs quickly into the skin.
• Fragrance-free formula suitable for sensitive skin.
• Contains evidence-based ingredients like retinol and niacinamide.
The Bad
• Some users experienced irritation or sensitivity around the eyes.
• Packaging design may make it difficult to dispense the serum.
• Results may take a few weeks to become noticeable.
Key Active Ingredients: Retinol,Niacinamide / Targeted Skin Concerns: Anti-aging,Hydration,Brightening / Fragrance Free: true / Vegan: false
8.5
Listful
Score
TNS Advanced+ Serum
$236.00
For those serious about anti-aging, TNS Advanced+ Serum is a standout option that delivers significant improvements in skin texture and firmness. Our experience shows its peptide and botanical blend achieves visible results in just two weeks, although its high price and occasional packaging malfunctions earned it an 8.5/10 score. This serum offers substantial benefits for those ready to invest in a high-impact product, tackling wrinkles and sagging while deeply hydrating and brightening the skin.
The Good
• Noticeable improvement in skin texture and firmness within weeks.
The Bad
• High price point may be prohibitive for some users.
• Dual-chamber pump design can occasionally malfunction.
Key Active Ingredients: Peptides,Botanicals / Targeted Skin Concerns: Anti-aging,Hydration,Brightening / Fragrance Free: true / Vegan: false
Brightening Boosters: Achieving a Radiant Glow
Serums with vitamin C and other brightening ingredients for a luminous skin tone.
7
Listful
Score
Vitamin C Complex Serum
$21.00
The Vitamin C Complex Serum from Naturium is a lightweight, easily absorbed booster perfect for daily use in your skincare routine. We found that it excels in brightening and anti-aging, thanks to its powerful combination of Vitamin C and Hyaluronic Acid. While it scored a 7/10 in our ratings, it may not be ideal for those with sensitive skin due to reports of irritation. Nevertheless, its fragrance-free and vegan-friendly formula makes it a solid choice for many.
The Good
• The serum is lightweight and absorbs easily, making it comfortable for daily use.
The Bad
• Some users with sensitive skin have reported experiencing irritation or burning sensations upon application.
Key Active Ingredients: Vitamin C,Hyaluronic Acid / Targeted Skin Concerns: Anti-aging,Brightening / Fragrance Free: true / Vegan: true
7.5
Listful
Score
Vitamin C Brighten + Firm Serum
$101.00
With its high score of 7.5/10, the Vitamin C Brighten + Firm Serum delivers a concentrated dose of the stable compound ethylated L-ascorbic acid. Our testing confirms its prowess in enhancing collagen production and photoprotection, although some users find its sticky texture off-putting. At $101.00, its price might be a hurdle, but its efficacy in anti-aging and brightening is hard to ignore, especially for more seasoned skincare enthusiasts.
The Good
• Contains 20% ethylated L-ascorbic acid, a stable form of Vitamin C that boosts collagen production and provides photoprotection.
The Bad
• Some users find the serum's texture to be sticky and oily, making application less comfortable.
• Priced at $101.00, it may be considered expensive compared to other Vitamin C serums on the market.
Key Active Ingredients: Vitamin C,Peptides,Botanicals / Targeted Skin Concerns: Anti-aging,Brightening / Fragrance Free: true / Vegan: true
9.5
Listful
Score
C E Ferulic by SkinCeuticals
$185.00
Recognized for its almost perfect score of 9.5/10, the C E Ferulic by SkinCeuticals is a luxurious choice for those willing to invest. During our review, its blend of Vitamin C, E, and Ferulic Acid proved excellent at reducing hyperpigmentation and brightening skin. However, the high price and potential irritation for sensitive types should be factored. While the scent might not appeal to all, the effectiveness against aging signs speaks volumes.
The Good
• Effectively brightens skin and reduces hyperpigmentation.
• Contains a potent blend of antioxidants including Vitamin C, Vitamin E, and Ferulic Acid.
• Lightweight and fast-absorbing texture suitable for layering under makeup.
The Bad
• High price point may be prohibitive for some consumers.
• Unpleasant scent that some users find off-putting.
• May cause irritation or breakouts in sensitive skin types.
Key Active Ingredients: Vitamin C / Targeted Skin Concerns: Anti-aging,Brightening / Fragrance Free: false / Vegan: false
7
Listful
Score
Perfectionist Pro Rapid Brightening Treatment Serum
$95.00
Estée Lauder's Perfectionist Pro Rapid Brightening Treatment Serum offers a lightweight formula that quickly absorbs, making it great for layering. During our review, many saw reduced dark spots and enhanced radiance, but its fragrance and $95.00 price tag could deter sensitive users. Scoring a 7/10, it’s a premium option for those prioritizing a bright, even complexion, albeit with some considerations for budget and fragrance tolerance.
The Good
• Lightweight formula absorbs quickly without leaving a sticky residue.
• Some users report a noticeable brightening effect and reduction in dark spots.
The Bad
• Contains fragrance, which may not be suitable for sensitive skin.
• High price point may be a concern for budget-conscious consumers.
Key Active Ingredients: Vitamin C,Botanicals / Targeted Skin Concerns: Brightening,Anti-aging / Fragrance Free: false / Vegan: false
6.5
Listful
Score
MULTI CORREXION Revive + Glow Daily Serum
$26.99
Despite its 6.5/10 score, the MULTI CORREXION Revive + Glow Daily Serum is an affordable alternative for those seeking brightening benefits. We found its Vitamin C formula brightens effectively, though some users noted a sticky residue and mild tingling. While it's budget-friendly, its fragrance could be a concern. Nevertheless, it's an accessible choice for daily use if you're looking to brighten and tighten your complexion on a budget.
The Good
• Contains a potent Vitamin C formula known for its brightening and antioxidant properties.
• Affordable price point compared to higher-end competitors.
• Lightweight texture that absorbs quickly without leaving a greasy residue.
The Bad
• Some users report a sticky feeling after application.
• Some users experience a mild tingling sensation upon application.
• Contains fragrance, which may be bothersome to individuals sensitive to scents.
Key Active Ingredients: Vitamin C / Targeted Skin Concerns: Brightening,Anti-aging / Fragrance Free: false / Vegan: false
6
Listful
Score
TruSkin Vitamin C Facial Serum
$15.59
TruSkin's Vitamin C Facial Serum, priced at $15.59, offers a budget-friendly entry into Vitamin C serums with a 6/10 rating. Our experience shows it’s equipped with Niacinamide and Retinol for broad skincare benefits. However, watch out for potential dryness or product waste from its dispenser. Its fragrance-free and vegan formula makes it an attractive option for those exploring comprehensive skin treatment without heavy financial investment.
The Good
• Contains a blend of Vitamin C, Niacinamide, Hyaluronic Acid, and Retinol for comprehensive skincare benefits.
• Affordable price point compared to other leading brands.
The Bad
• Some users report a tightening or drying sensation after application.
• Dispenser design may release more product than needed per use.
Key Active Ingredients: Vitamin C,Retinol,Hyaluronic Acid,Niacinamide / Targeted Skin Concerns: Anti-aging,Brightening / Fragrance Free: true / Vegan: true
7
Listful
Score
CeraVe Vitamin C Serum
$19.19
CeraVe's Vitamin C Serum is a cost-effective choice for brightening and hydration, scoring 7/10 in our review. Its 10% pure vitamin C formula targets dullness with a light, non-greasy application, complemented by hydrating ceramides and hyaluronic acid. Some users reported quick oxidation and packaging issues, but overall, it's an affordable route to achieving a luminous and smooth complexion, keeping skin feeling soft and refreshed.
The Good
• Contains 10% pure vitamin C for effective skin brightening.
• Lightweight texture that absorbs quickly without leaving a greasy residue.
• Formulated with ceramides and hyaluronic acid to maintain skin hydration and barrier.
The Bad
• Contains denatured alcohol, which may cause irritation for sensitive skin.
• Packaging can make it difficult to dispense the correct amount of product.
• Some users report the serum oxidizes quickly, reducing its effectiveness over time.
Key Active Ingredients: Vitamin C,Hyaluronic Acid,Peptides / Targeted Skin Concerns: Brightening,Anti-aging,Hydration / Fragrance Free: true / Vegan: false
6.5
Listful
Score
Naturium Vitamin C Complex Serum
$13.99
Naturium Vitamin C Complex Serum is perfect for budget-conscious skincare enthusiasts seeking brightening effects. Earning a 6.5/10 rating, this serum combines vitamin C with botanicals for vibrant, healthy skin. Be cautious if sensitive, as some noted irritation, and the precise concentration of vitamin C isn't disclosed. Despite this drawback, its affordability and vegan-friendly ingredients make it a commendable addition to a brightening regimen.
The Good
• Lightweight and non-sticky texture that absorbs quickly into the skin.
• Affordable price point compared to other vitamin C serums.
The Bad
• Some users with sensitive skin reported experiencing irritation or burning sensations.
• Lack of transparency regarding the exact concentration of vitamin C used in the formulation.
Key Active Ingredients: Vitamin C,Hyaluronic Acid,Botanicals / Targeted Skin Concerns: Anti-aging,Brightening,Hydration / Fragrance Free: true / Vegan: true
Introducing New Serums: Timing and Tips
Guidance on when to introduce new products and tips for optimal absorption.
8
Listful
Score
Lotus AHA Gentle Resurfacing Serum
$69.00
Introduce a luxurious glow to your skincare with Lotus AHA Gentle Resurfacing Serum, recognized for smoothing texture and enhancing radiance. Priced on the higher side, this 8/10 rated serum combines AHAs and prickly pear flower extract to combat dark spots, and is suitable for all skin types. While not the cheapest option, its ability to boost skin clarity and tone, free from parabens and sulfates, makes it a worthy investment for those committed to anti-aging and brightening benefits.
The Good
• Contains AHAs and prickly pear flower extract that visibly even texture, boost radiance, and reduce the look of dark spots and lines.
• Suitable for all skin types and tones.
• Free of parabens and sulfates.
The Bad
• The serum is a bit pricey.
Key Active Ingredients: AHA,Botanicals / Targeted Skin Concerns: Anti-aging,Brightening / Fragrance Free: false / Vegan: true
The Ultimate Serum Application Order: A Step-by-Step Guide
A clear and concise guide to layering serums for maximum effectiveness.
8
Listful
Score
Active Serum
$92.00
Try the Active Serum if you're battling acne and uneven skin texture. This product scored 8/10 in our testing for its efficacy in smoothing skin and combating breakouts, thanks to its AHA and botanical mix. While it’s a pricier option, its anti-aging and brightening qualities are worth noting. Be cautious if you have sensitive skin, as the alcohol and menthol content may cause irritation.
The Good
• Effectively reduces acne and improves skin texture.
The Bad
• Contains alcohol and menthol, which may cause irritation for sensitive skin.
• Higher price point compared to similar products.
Key Active Ingredients: AHA,Botanicals / Targeted Skin Concerns: Anti-aging,Brightening,Acne treatment / Fragrance Free: false / Vegan: true
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